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ONTOLOGY REPORT - ANNOTATIONS

Term:immune response to tumor cell
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Accession:GO:0002418 term browser browse the term
Definition:An immune system process that functions in the response of an organism to a tumor cell.

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immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam15 ADAM metallopeptidase domain 15 involved_in ISO (PMID:22505472) UniProt PMID:22505472 NCBI chrNW_004624885:2,441,298...2,451,061
Ensembl chrNW_004624885:2,441,217...2,451,057 		JBrowse link
G Prf1 perforin 1 involved_in ISO (MGI:66009|PMID:8164737) UniProt PMID:8164737 MGI:66009 NCBI chrNW_004624754:4,679,451...4,681,627
Ensembl chrNW_004624754:4,679,521...4,681,627 		JBrowse link
natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkg7 natural killer cell granule protein 7 involved_in ISO (MGI:6506882|PMID:32839608) UniProt PMID:32839608 MGI:6506882 NCBI chrNW_004624832:3,501,924...3,502,750
Ensembl chrNW_004624832:3,501,973...3,504,773 		JBrowse link
negative regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) UniProt PMID:22842346 MGI:5437532 NCBI chrNW_004624733:32,521,318...32,527,499 JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) UniProt PMID:22842346 MGI:5437532 NCBI chrNW_004624733:32,521,318...32,527,499 JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605 		JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated ISO RGD PMID:10232613 RGD:2303754 NCBI chrNW_004624730:61,153,753...61,176,859 JBrowse link
negative regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor involved_in ISO (PMID:32818467) UniProt PMID:32818467 NCBI chrNW_004624739:12,939,183...12,987,574
Ensembl chrNW_004624739:12,942,165...12,987,973 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:28813410), (PMID:28813417) UniProt PMID:28813410 PMID:28813417 NCBI chrNW_004624736:9,991,851...10,017,047
Ensembl chrNW_004624736:9,996,156...10,013,814 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (MGI:6508513|PMID:28405502)
(MGI:6508501|PMID:21469114)
(PMID:32818467)		 UniProt PMID:21469114 PMID:28405502 PMID:32818467 MGI:6508501 MGI:6508513 NCBI chrNW_004624832:4,404,818...4,444,551
Ensembl chrNW_004624832:4,431,903...4,444,651 		JBrowse link
G Pdcd1 programmed cell death 1 involved_in ISO (PMID:38377992) UniProt PMID:38377992 NCBI chrNW_004624847:5,732,922...5,741,908
Ensembl chrNW_004624847:5,732,767...5,742,269 		JBrowse link
G Ufl1 UFM1 specific ligase 1 involved_in ISO (PMID:38377992) UniProt PMID:38377992 NCBI chrNW_004624810:8,804,330...8,832,460
Ensembl chrNW_004624810:8,805,964...8,832,358 		JBrowse link
positive regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40lg CD40 ligand ISO RGD PMID:19016771 RGD:2313413 NCBI chrNW_004624808:10,472,028...10,484,407
Ensembl chrNW_004624808:10,472,572...10,484,338 		JBrowse link
G Gsdme gasdermin E involved_in ISO (PMID:32188940) UniProt PMID:32188940 NCBI chrNW_004624739:5,790,372...5,879,979
Ensembl chrNW_004624739:5,798,771...5,871,088 		JBrowse link
G Hrg histidine rich glycoprotein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:70,070,302...70,086,256 JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624806:11,324,239...11,390,487
Ensembl chrNW_004624806:11,324,344...11,388,206 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (PMID:15811952)
(MGI:3689781|PMID:15811952)		 HGNC-UCL
UniProt		 PMID:15811952 MGI:3689781 NCBI chrNW_004624880:2,229,201...2,240,068 JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:7903063) UniProt PMID:7903063 NCBI chrNW_004624730:37,787,772...37,794,871
Ensembl chrNW_004624730:37,787,909...37,794,940 		JBrowse link
G Il12b interleukin 12B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624733:30,146,050...30,156,144
Ensembl chrNW_004624733:30,146,050...30,154,589 		JBrowse link
G LOC101712173 poliovirus receptor homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,582,636...1,596,528 JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,713,786...1,739,158
Ensembl chrNW_004624907:1,713,443...1,740,627 		JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101700189 major histocompatibility complex class I-related gene protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624771:1,275,364...1,298,967
Ensembl chrNW_004624771:1,275,302...1,293,552 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:19282870) UniProt PMID:19282870 NCBI chrNW_004624773:19,950,353...19,968,029
Ensembl chrNW_004624773:19,950,303...19,962,575 		JBrowse link
positive regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:7774619) MGI PMID:7774619 NCBI chrNW_004624780:15,287,426...15,292,292
Ensembl chrNW_004624780:15,287,433...15,292,292 		JBrowse link
G Fbxo38 F-box protein 38 involved_in ISO (PMID:30487606) UniProt PMID:30487606 NCBI chrNW_004624774:7,798,407...7,849,840
Ensembl chrNW_004624774:7,798,369...7,850,056 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:10663613) BHF-UCL PMID:10663613 NCBI chrNW_004624889:2,736,727...2,746,333 JBrowse link
regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (MGI:5470371|PMID:23108142) UniProt PMID:23108142 MGI:5470371 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15089
    immune system process 2103
      immune response 1306
        immune response to tumor cell 26
          T cell mediated immune response to tumor cell + 12
          natural killer cell mediated immune response to tumor cell + 9
          negative regulation of immune response to tumor cell + 8
          positive regulation of immune response to tumor cell + 14
          regulation of immune response to tumor cell + 23
          tolerance induction to tumor cell + 0
Path 2
Term Annotations click to browse term
  biological_process 15089
    response to stimulus 8165
      response to biotic stimulus 1361
        response to tumor cell 42
          immune response to tumor cell 26
            T cell mediated immune response to tumor cell + 12
            natural killer cell mediated immune response to tumor cell + 9
            negative regulation of immune response to tumor cell + 8
            positive regulation of immune response to tumor cell + 14
            regulation of immune response to tumor cell + 23
            tolerance induction to tumor cell + 0
paths to the root